Apigenin is a naturally occurring flavonoid found in a variety of plants, including parsley, celery, chamomile, and oranges. Known for its vibrant yellow color, apigenin has been traditionally used in herbal medicine for its calming and anti-inflammatory properties.

  Supplemental Benefits of Apigenin:

Promotes Relaxation and Sleep: Apigenin is known for its calming effects and ability to promote relaxation. It may help reduce anxiety and improve sleep quality by interacting with the GABA receptors in the brain, which play a key role in regulating sleep and mood.

Supports Cognitive Function: Research suggests that apigenin may have neuroprotective effects, potentially aiding in the prevention of neurodegenerative conditions. It may also enhance memory and cognitive function by reducing oxidative stress and inflammation in the brain.

Antioxidant Activity: As a powerful antioxidant, apigenin helps neutralize free radicals in the body, reducing oxidative stress and protecting cells from damage. This activity contributes to overall cellular health and longevity.

Supports Cardiovascular Health: Apigenin may improve heart health by reducing blood pressure, lowering cholesterol levels, and preventing the oxidation of LDL cholesterol, which is a major risk factor for cardiovascular disease.

Potential Anti-Cancer Properties: Some studies suggest that apigenin may inhibit the growth of cancer cells and induce apoptosis (programmed cell death) in certain types of cancer. While research is still ongoing, apigenin’s ability to interfere with cancer cell proliferation is promising.

Hormonal Balance: Apigenin may help regulate hormone levels, particularly in women, by modulating estrogenic activity. This can be beneficial for managing symptoms related to hormonal imbalances, such as those experienced during menopause.

  Forms and dosage:

Apigenin: If a supplement label simply says “Apigenin” without specifying any additional details, it likely indicates that the supplement contains either pure apigenin or an unstandardized extract, focusing on delivering a specific dosage of the compound.

Apigenin Extract: In apigenin supplements, the concentration of apigenin in extracts can vary, but common percentages typically range from 10% to 98%.  Lower Concentrations (10%-20%): These extracts may contain a broader spectrum of plant compounds along with apigenin. They are less concentrated but might offer additional benefits from other phytochemicals in the source plant.  Higher Concentrations (50%-98%): These are more refined extracts where apigenin is the primary component. Concentrations like 98% are considered highly pure and are often used for more targeted supplementation, delivering a potent dose of apigenin.

“Natural Apigenin”: The label “natural apigenin” suggests that the apigenin in the supplement is derived directly from a natural source, such as plants (like chamomile or parsley). However, it’s worth noting that most apigenin on the market is naturally derived, so the distinction might not be as significant as the label suggests. The “natural” label is primarily a marketing term to appeal to consumers who prefer products that emphasize their natural origins.

Daily dose:  50 – 300 mg.